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Recombinant Human FGF R4 - Fc Chimera hcx

Apollo's FGF R4 - Fc Chimerahcx contains 15-30% carbohydrate by weight, has N-linked oligosaccharides, shown by a drop in observed MW on SDS-PAGE after treatement with PNGase F, and may have O-linked oligosaccharides.

Click here to enlarge FGF R4 - Fc Chimera densitometry imageDensitometry of protein isoforms visualized by 2-DE. Spot trains are normal in human proteins and highlight the presence of multiple isoforms which differ according to their level of post-translational modification. The triangle indicates the theoretical MW and pI of the protein.

Fibroblast growth factors (FGFs) belong to a large family (23 human members) of mitogenic factors that signal by binding to the FGF receptors (FGFRs) along with heparin and heparin-like glycosaminoglycans (HLGAGs). FGFs have major roles in hematopoiesis, development, wound repair, angiogenesis and tumor growth. There are multiple receptor splice variants that produce a number of isoforms of the four FGFRs.

1. Eswarakumar VP, et al. (2005) Cytokine Growth Factor Rev. 16: 139-49.
2. Ezzat S & Asa SL (2005) Horm Metab Res. 37: 355-60.

For more information on this protein, please click on the protein name below to download a PDF version of the product sheet.

FGF R4 - Fc Chimera:
Protein Species Source % Carbohydrate Catalogue No. Size Price (USD)  
FGF R4 - Fc Chimera Human Human 15-30 2104G 20 ug $200.00 Add to Cart Click here to view cart
FGF R4 - Fc Chimera Human Human 15-30 2104H 25 ug $240.00 Add to Cart Click here to view cart

For further technical information about Apollo's range of hcx proteins, please click here.