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Recombinant Human IL-12 
Apollo's IL-12 hcx contains the alpha and beta chains of human IL-12. It has N- and O-linked oligosaccharides, shown by a drop in observed MW on SDS-PAGE after treatment with PNGase F and a further drop after treatment with a glycosidase cocktail. Apollo's IL-12 hcx alpha chain contains 15-35% carbohydrate by weight. Apollo's IL-12 hcx beta chain contains 0-25% carbohydrate by weight.
Densitometry of protein isoforms visualized by 2-DE. Spot trains are normal in human proteins and highlight the presence of multiple isoforms which differ according to their level of post-translational modification. The triangle indicates the theoretical MW and pI of the protein.
1D SDS-PAGE of Apollo's hcx protein before and after treatment with glycosidases to remove oligosaccharides. A drop in the observed MW after treatment indicates the presence of glycosylation. For more details, please see product sheet.
1. Gately et al. (1998) Ann Rev Immunol 16:495-521
Additional Resources:
» Bioactivity Data: IL-12
» Poster: IL-12 hcx has enhanced pro-inflammatory activity
» Brochure: HCX Proteins in Cancer Research
For more information on this protein, please click on the protein name below to download a PDF version of the product sheet.
| IL-12: | |||||||
| Protein | Species | Source | % Carbohydrate | Catalogue No. | Size | Price (USD) | |
 IL-12 |
Human | Human | 15-35 on alpha chain 0-25 on beta chain |
4012C | 5 ug | $440.00 | Add to Cart
 |
| IL-12 |
Human | Human | 15-35 on alpha chain 0-25 on beta chain |
4012D | 10 ug | $865.00 | Add to Cart
|
| IL-12 |
Human | Human | 15-35 on alpha chain 0-25 on beta chain |
4012H | 25 ug | $1440.00 | Add to Cart
|
For further technical information about Apollo's range of hcx proteins, please click here.