
TGF-beta 1 is a member of the TGF beta superfamily, which includes at least five other isoforms. It is synthesized as a 390 amino acid glycoprotein and contains a 29 amino acid signal sequence and a 249 amino acid latency associated pro-peptide sequence. Apollo purified TGF-beta 1hcx consists of the mature peptide only, the latency associated peptide is cleaved from the mature protein and removed during purification.
TGF-beta 1 is a pleotropic cytokine that regulates various functions, such proliferation and differentiation, of immune and non-immune somatic cells via paracrine and autocrine mechanisms. It is a potent cell growth inhibitor of fibroblasts, hepatocytes, keratinocytes, and endothelial and neuronal cells.
1. Piek E. et al. (1999) The FASEB Journal 13:2105-2124
For more information on this protein, please click on the protein name below to download a PDF version of the product sheet.
| TGF-beta 1: | |||||||
| Protein | Species | Source | % Carbohydrate | Catalogue No. | Size | Price (USD) | |
| Human | Human | <5 | 3022B | 2 ug | $480.00 | Add to Cart
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For further technical information about Apollo's range of hcx proteins, please click here.